Quercetin-Biyaha-Layfiga ah ee Bixinta Nafaqada Sare

Codsiyada Caafimaadka ee kala duwan

1. Xeerka Gulukooska dhiigga
Qurcetin-ka biyaha ku milma ayaa rajo cusub siiya shakhsiyaadka ka walaacsan caafimaadka gulukoosta dhiigga. Cilmi-baaris uu sameeyay Machadka Cilmi-baarista Miraha ee Zhengzhou, Akadeemiyada Shiinaha ee Sayniska Beeraha, ayaa shaaca ka qaaday in quercetin, oo ay weheliso flavonoids kale oo miro ah, ay si isku mid ah u joojin karto dhaqdhaqaaqa α-glucosidase. α-Glucosidase waxay door muhiim ah ka ciyaartaa hydrolysis-ka karbohaydraytyada, iyo joojinta dhaqdhaqaaqeeda waxay si wax ku ool ah u xannibi kartaa dheefshiidka iyo nuugista karbohayhaydraytyada, taas oo gacan ka geysaneysa xakameynta heerarka gulukooska dhiigga ee ka dib. Iyada oo ay si fiican u milmayn iyo nuugista, quercetin-biyoodka-milmi kara waxay si hufan uga qayb qaadan kartaa joojinta α-glucosidase, iyada oo siinaya taageero adag oo loogu talagalay horumarinta alaabooyinka shaqeynaya ee loogu talagalay in lagu xakameeyo gulukooska dhiigga ee postprandial. Tani waxay saameyn weyn ku leedahay maaraynta caafimaadka maalinlaha ah ee bukaanka sonkorowga ama kuwa leh heerarka gulukoosta dhiigga ee isbeddelaya.
2. Ilaalinta Caafimaadka Beerka
Qurcetin-ka biyaha ku milma ayaa sidoo kale iftiimaya ilaalinta caafimaadka beerka. Daraasad ay sameeyeen kooxda Professor Peng Cheng oo ka tirsan Jaamacadda Chengdu ee Daawada Dhaqanka ee Shiinaha ayaa muujisay in quercetin ay hagaajin karto beerka dufanka leh ee khamriga leh iyada oo dhexdhexaadinaysa beddelka nukliyeerka ee TFEB si loo magdhabo autophagy-ga aan ku filnayn. Nuugista la xoojiyey ee quercetin biyo-milmi leh ayaa u oggolaanaysa inay si dhakhso leh oo waxtar leh u gaadho beerka, xoojinta shaqada autophagic ee unugyada beerka, kor u qaadida dheef-shiid kiimikaadka dufanka beerka, iyo fududaynta baabi'inta walxaha waxyeelada leh. Tani waxay gacan ka geysaneysaa ka hortagga iyo hagaajinta cudurrada kala duwan ee beerka, sida beerka dufanka leh iyo cudurrada beerka khamriga, iyadoo yareyneysa waxyeelada khamriga iyo waxyaabaha kale ee beerka.
3. Kor u qaadista timaha
Timaha daadanaya ayaa ah walaac caadi ah oo ay qabaan dad badan, quercetin-ka biyaha ku milma ayaa bixisa xal cusub oo dhibaatadan ah. Daraasad iskaashi ah oo ay sameeyeen kooxda Professor Qu Jing oo ka socota Machadka Cilmi-baarista Sayniska, Akademiyada Sayniska ee Shiinaha, ayaa ogaatay in quercetin ay si wax ku ool ah u horumarin karto dib-u-soo-nooleynta timaha iyada oo la kicinayo waddada HIF-1 ee unugyada endothelial ee microenvironment timaha follicle. Qurcetin-ka biyaha ku milma waxay si aan kala go 'lahayn u geli kartaa dhiigga oo waxay gaari kartaa aagga follicle timaha, iyadoo si buuxda u fulisa saameynteeda nidaamsan ee microenvironment timaha follicle. Waxay kicisaa kala soocida iyo badinta unugyada stem follicle timaha, taas oo kor u qaadeysa koritaanka timaha. Haddii timaha daataan ay sababto walbahaarka, dheellitirnaan la'aanta hoormoonka, ama arrimo kale, quercetin-ka biyaha-milmi kara waxay ballan qaadaysaa daaweyn badbaado leh oo waxtar leh.
4. Kobcinta habka difaaca jirka
Quercetin lafteedu waxay leedahay hawlo immunomodulatory ah oo gaar ah, sida kor u qaadida firfircoonida makrophage iyo dheecaanka arrimaha difaaca ee la xidhiidha. Imaatinka quercetin-biyoodku waxay sii kordhinaysaa faa'iidooyinkan. Biyo la'aanteeda aadka u fiican waxay hubisaa qaybinta isku midka ah ee jidhka dhexdiisa, taas oo awood u siinaysa inay si sax ah ugu dhaqanto qaybaha kala duwan ee nidaamka difaaca. Waxay wanaajisaa waxqabadka unugyada difaaca waxayna kor u qaadaysaa dheecaanka difaaca jirka sida buro necrosis factor-α iyo interferon-γ, taasoo ka caawinaysa jidhku inuu si fiican uga difaaco cudurada dibadda wuxuuna si weyn u xoojiyaa difaaca guud. Tani waxay awood u siinaysaa shakhsiyaadka inay yeeshaan iska caabin xooggan marka ay la kulmaan khataraha caafimaadka sida fayraska hargabka iyo caabuqyada bakteeriyada.